Recently I did an installation of the Citrix WI 5.4 and noticed a delay on displaying the first page after restarting the server, this problem happened also when I restarted the IIS Service.  I found CTX117273:

Background

After restarting IIS, or rebooting the Web Interface server, it takes up to one minute to get the Welcome page for the first user.

Procedure

• Install Web interface 5.0.1.

• Restart IIS.

• Connect to a Web Interface site. The first connection is very slow and it takes up to one minute to get the Welcome page for the first user.

• All other connections are normal until you restart IIS again.

Workaround

This issue is caused by a CRL check sent to Verisign. If the Web Interface server cannot access the internet, the CRL check fails and times out.

• Check in IIS for the ASP.net version that is in use with the Web Interface site.
  Modify Aspnet.config  in the following directory
  C:WINDOWSMicrosoft.NETFrameworkv2.0.50727 (If Web Interface uses .Net framework v2.0.50727)

• Add the following lines to your ASPNET.CONFIG or APP.CONFIG file:
  <?xml version=”1.0″ encoding=”utf-8″?>
  <configuration>
  <runtime>
  <generatePublisherEvidence enabled=”false”/>
  </runtime>
  </configuration>