If you’ve just stumbled upon this article, I recommend you start from the beginning by clicking the Part 1 link below. For easy reading, I’ve broken this blog post into four parts:
Part 1: Microsoft SQL Server Installation
Part 2: Management and Reporting Server Installation
Part 3: Publishing Server Installation, Registration, and Load Balancer Configuration <– YOU ARE HERE
Part 4: Sequencing and Client Installation

On the Publishing Servers (WS12APPV502 and WS12APPV503 in my topology) complete the App-V installation, using the following processes. Repeat this same process for any additional publishing servers. To ease deployment, I’ve created a Prerequisites PowerShell quick reference. Copy the following to paste into an elevated PowerShell prompt:

Install-WindowsFeature Web-Server
Install-WindowsFeature Web-Asp-Net
Install-WindowsFeature Web-Net-Ext
Install-WindowsFeature Web-ISAPI-Ext
Install-WindowsFeature Web-ISAPI-Filter
Install-WindowsFeature Web-Windows-Auth
Install-WindowsFeature Web-Mgmt-Console
Install-WindowsFeature NET-Framework-45-ASPNET
Install-WindowsFeature Web-Asp-Net45

Open an Elevated PowerShell prompt and paste the script block:

You should see several confirmations that the Roles and Features were installed. When completed, close the PowerShell prompt:

Download and install Microsoft C++ 2010 x64 Runtime Redistributable (vcredist_64):

Accept the license terms and click Install:

Click Finish:

Download and install Microsoft C++ 2010 x86 Runtime Redistributable (vcredist_86):

Accept the license terms and click Install:

Click Finish:

Mount the App-V 5 Installation Media and navigate to Drive:\App-V 5.0 Server. Launch APPV_SERVER_SETUP:

Click Install:

Accept the license terms and click Next:

Select Use Microsoft Update and click Next

Select Publishing Server and click Next:

Click Next:

Enter the URL and Port Binding for the management server (http://ws12appv501:552). Enter the Publishing Server Port Binding 554 and click Next:

Click Install:

Close the App-V Installer. This completes the necessary installations on the publishing servers. Repeat this process for any additional publishing servers.

Once all publishing servers have been installed, go back to the management server and complete the following configuration. On the left, select SERVERS:

Click Register New Server:

Enter the domain\servername (ws12\WS12APPV502) and click Check. Click Add:

Repeat this process to add any additional servers (ws12\WS12APPV503):

Click Close:

To configure the hardware load balancer (i.e. Citrix NetScaler), create a new virtual server with an HTTP 554 Port Binding:

Add a new service for each publishing server with an HTTP 554 port binding. Use TCP for the service monitor:

Create Services for any additional publishing servers:

Review and ensure that each service is up and operational. Create the Virtual Server and close the dialog:

Review the LB Virtual Server and save the configuration:

To review any section, please choose from the following:

Part 1: Microsoft SQL Server Installation
Part 2: Management and Reporting Server Installation
Part 3: Publishing Server Installation, Registration, and Load Balancer Configuration <– YOU ARE HERE
Part 4: Sequencing and Client Installation

If you have any questions, comments, or just want to leave feedback, please do so below. Thanks for reading!

–youngtech